THE bonefill® It is a 100% pure bone mineral, originating from bovine femur, produced through a unique multi-stage purification process. Unlike other products, bonefill® It does not undergo heat treatment, being purified only through a chemical treatment. In comparison, Cerabone® undergoes a heat treatment process at 1200°C.

In the bonefill® manufacturing process, fresh bone is crushed and subjected to a series of baths that solubilize organic structures, such as remaining cells, fibers, and proteins, leaving only the mineral portion. This prevents the induction of possible immunogenic reactions in the body. This innovative approach ensures maximum safety and results in exceptionally high purity of bonefill®, guaranteeing highly satisfactory results.

For decades, the bonefill® It has been used in regenerative procedures, both in Brazil and in several other countries. In the national market, ANVISA (Brazilian Health Regulatory Agency) began regulating it in the early 2000s, and since then the product has been duly registered, meaning it has been in use for more than [number missing]. 20 years of your presence in the market!

Currently the family of bonefill® granules are composed of bonefill® dense, bonefill® mix and bonefill® porous.

THE bonefill® dense It is produced through the decalcification process of the portion cortical of the bovine femoral head, the bonefill® porous,, is produced through the same decalcification process applied to the spongy portion of the bovine femoral head, and the bonefill® mix It is the combination of the spongy and cortical portions of the xenograft (approximate proportion). 70:30).

The great advantage of bonefill® Mix, is its combination of bone particles spongy and cortical in its composition, since the spongy particles provide a larger area for bone formation, while the cortical particles ensure superior long-term volumetric stability.

The cerabone® Because it is sintered bone (>1250°C), it lacks a system of interconnected micropores, which does not occur in  bonefill® porous or mix, which more closely resemble native bone. The bonefill® porous or mix It is significantly more porous than Cerabone®, which creates more space for vascularization and the permeation of new bone. Furthermore, being more hydrophilic, it… bonefill® porous or mix It exhibits greater fluid absorption and capillary rise.

We should only use the raw material as a comparison, since both are produced through the decalcification process of the portion cortical from the bovine femoral head. We emphasize that the manufacturing processes are distinct, resulting in products with distinct properties. Therefore, we can offer… bonefill® dense as a replacement for Lumina Bone (Criteria).

NoAbsolutely not! Autoclaving can cause moisture to accumulate in the product, which is highly porous, and can also alter its delicate crystalline structure. Furthermore, ANVISA (Brazilian Health Regulatory Agency) does not authorize resterilization in dental offices. For this reason, the BionovationAs the manufacturer, we cannot assume responsibility for the product.

Validity is one of our main differentiators. While some domestic companies market products with a shelf life of 2 years and other imported companies, such as Cerabone® (Botiss), offer a shelf life of 3 years, the bonefill® It is sold with a shelf life of 5 years from the date of manufacture.